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¹ 2, 2013

  Editorial
   
Title:

USING OF MICROORGANISMS IN THE DEGRADATION OF ENVIRONMENTAL POLUTOUTS

   
Authors: Ivanov A.A.; Matrosova L.E.
   
Address: Federal Center of Toxicological, Radiation and Biological Safety, Kazan.
   
Abstract:
   
   
  Toxicology
   
Title:

STUDY OF ACUTE AND SUBACUTE TOXYCITY OF THE "DEZAKAR" DRUG

   
Authors: Saypullaev M.S.; Kabardiev S.SH.; Koychuev A.U.
   
Address: Caspian Area Research Veterinary Institute., Makhachkala
   
Abstract: One of the important veterinary actions for preservation of animals and birds and increase of their efficiency is disinfection of objects of veterinary supervision. For this purpose it is necessary to use new highly effective, ecologically safe, ìàëîòîêñè÷íûå for health of people and animals preparations. In given article results of studying sharp and ïîäîñòðîé toxicity of solutions of a preparation of "Dezakar" for laboratory animals are resulted. On the basis of the spent experiences by us it is established that the preparation of "Dezakar" let out ÔÃÓÏ «the Shchelkovo bioindustrial complex» concerns "moderately dangerous substances (3 class of danger) possessing toxicity (Ld50) 4,19g/kg of weight of a body and as possesses"moderately cumulative properties (Êêóì-3,8) which is directed on accustoming of an organism of animals.
   
Keywords: toxicity, method Cerberus, srednesmertelnaya dose poisoning, cumulative properties
   
  Infectious pathology
   
Title:

INFLUENCE OF IMMUNOMODULATORS ON EFFICIENCY OF CALVES VACCINATION AGAINST RHINOTRACHEITIS AND PARAINFLUENZA 3

   
Authors: Setdekov R.A., Yusupov R.H., Gumerov V.G.
   
Address: Federal Center of Toxicological, Radiation and Biological Safety.
   
Abstract: The performed investigations showed that using vaccine along with immunomodulating means like ximedone or rhidostin promotes increasing of postvaccination antiviral immunity and immunobiological resistance by intensification of cellular and humoral immunity and general non-specific resistence of calves. These findings give grounds to recommend the drugs in order to promote efficiency of specific prevention at infections rhinotracheitis and parainfluenza 3.
   
Keywords: calves, vaccine, immunomodulator, infections
   
   
   
Title:

STUDYING OF THE PROPHYLACTIC ACTION OF THE ACTINOMYCOTIC DRUG ON BIOCHEMICAL PARAMETERS OF CATTLE BLOOD SERUM

   
Authors: Bogoutdinov N.Sh.
   
Address: Saratovsky Research Veterinary Institute of Russian Academy of Agrarian Sciences.
   
Abstract: The goal of our study was the development of effective biological preparation against actimonycosis of cattle prepared from isolate obtained from pathological material. The efficiency of experimental preparation for prophylaxis of actinomycosis was estimated by biochemical changes in castles blood.
   
Keywords: actinomycosis, biologicals, biochemical parameters, serum
   
   
   
Title:

STUDYING OF SOME SEROLOGICAL, MORPHOLOGICAL AND PHYSICAL AND CHEMICAL PROPERTIES OF ANTIGENE CULTURAL OF THE VIRUS OF THE EQUINE INFECTIOUS ANEMIA

   
Authors: Ljulkova L.S.; Samujlenko A.J.
   
Address: Russian Academy for Agricultural Sciences All-Russia Research Technological Institute for Biological Industry.
   
Abstract: Data on studying of virus of the equine infectious anemia strain of "ZK-VNITIBP-VIEV" is presented. It is established that on morphology of virus particles, morphogenesis in cages of culture of fabrics of an embryo of a horse, on the serological  property the virus concerns family Retroviridae and possesses the biological properties corresponding to requirements, shown to industrial strain, used for manufacture of diagnostic preparations.
   
Keywords: the Equine Infectious Anemia (EIA), virus, morphology, immunological propertie
   
   
   
Title:

EPIZOOTOLOGICAL MONITORING OF PARAMYXOVIRUS INFECTION AMONG THE PIGEONS IN UKRAINE IN 2007 – 2011

   
Authors: Muzyka D.
   
Address: National Scientific Center «Institute of Experimental and Clinical Veterinary Medicine», Kharkiv, Ukraine.
   
Abstract: To date, 11 serotypes of avian paramyxoviruses (PMA-1 - PMA-11) are known. But of all the serotypes the particular dangerous for the poultry industry represents serotype 1 - Newcastle disease virus. Since 80-ies PMV serotype 1 isolated from pigeons, became known as "pigeon paramixoviruses of  serotype 1". In most cases they are not much different from other PMV-1, but the danger of this disease should be assessed in terms of the fact that pigeons are the main reservoir of highly virulent PMV-1 for poultry. The main goal of our research was to conduct epidemiological monitoring of paramyxovirus infection in pigeons, the study of these viruses circulating in the population of pigeons in different regions, and biological properties of isolated viruses. During the virological studies of biological material from sick pigeons from four regions of Ukraine since 2007 to 2011 we isolated 11 haemagglutinating viruses that have been identified as PMV serotype 1. According to the results of sequencing of all seven isolates all of them belong to the class II Newcastle disease virus (4 to II genotype, one-to-Ia genotype and two to VI).
   
Keywords: avian paramyxoviruses, Newcastle disease virus, pigeon paramixoviruses of serotype 1
   
  Non-transmittable diseases
   
Title:

BACKGROUND OF THE EMULSION CRS USAGE FOR DISEASE PREVENTION UDDER OF ANIMALS

   
Authors: Rakhmatullin E.K.; Golovin I.A.
   
Address: Ulyanovsk State Agricultural Academy P.A. Stolypin.
   
Abstract: Effective way of decrease in quantity of microbes in an udder is sanitary-and-hygienic premilking preparation and its processing after milking. In Open Society factory «Veterinary preparations» for preventive maintenance, treatments of cracks and dryness of a skin of an udder of cows it is developed preparation ÑÂÊ. By researches it is established, that preparation ÑÂÊ does not influence mechanisms of biochemical adaptation, a metabolism and function of internal bodies of animals. On the basis of results of biochemical researches of blood it is established, that preparation ÑÂÊ it is safe.
   
Keywords: emulsion, total protein, albumin, glucose, bilirubin, creatinine, urea, ALT, AST, LDH, alkaline phosphatase
   
   
   
Title:

STUDYING OF INFLUENCE OF A COMPLEX PREPARATION OF GEPATOVET ON FUNCTIONAL AND REGENERATOR ACTIVITY OF A LIVER MICE

   
Authors: Klimov P.V.
   
Address: All-Russian Research Institute for Veterinary Sanitation, Hygiene and Ecology of Russian Academy of Agrarian Sciences.
   
Abstract: In article results of studying of influence of a complex preparation of Gepatovet on the course of toxic hepatitis at mice induced tetrañhlormethany in vitro are reflected. It is established that application Gepatoveta promotes improvement of disintoxication and protein synthesis function of a liver and as accelerates reparativny processes in liver tissues that Gepatoveta allows to judge gepatoprotektivny activity. Gepatovet can be recommended in clinical practice as a gepatoprotektivny agent for treatment of toxic lesions of a liver.
   
Keywords: mice, tetrachlormethane, toxic hepatitis, gepatoprotektor
   
   
   
Title:

APPLICATION THE «NOORMOTROFIN» WITH THE PATHOLOGY OF THE RESPIRATORY ORGANS IN CALVES WITH THE SIGNS OF THE POST-NATAL IMMATURITY

   
Authors: 1Papunidi K. Kh.; 2Medetkhanov F.A.
   
Address: 1. Federal Center of Toxicological, Radiation and Biological Safety, Kazan.
2. The Kazan State Academy of Veterinary Medicine named after Bauman N.E.
   
Abstract: In the article are presented the results, obtained with the fulfillment of scientific research work on the application of plant preparation “Normotrofin” to calves - gipotrophic with the pathology of the respiratory organs. It is established that the studied means contributes to reconstruction of the morphological composition of blood and metabolic status of the organism of calves in the dynamics. It is shown that the application “Normotrofin” to calves with the signs of physiological immaturity with the associated pathology of the respiratory organs contributes to the elimination of the symptoms of disease, increase the indices of increase in the mass of body.
   
Keywords: «Normotrofin», calves – gipotrophic, bronchopneumonia, hematological indices, biochemical indices, mass of a body
   
   
   
Title:

DEVELOPMENT AND EFFECTIVENESS OF THE NEW METHOD IN THERAPY BY COWS SUFERRING FROM ACUTE ENDOMETRITIS

   
Authors: Konopeltsev I.G.; Muravina E.C.; Sapozhnikov A.F.
   
Address: Vyatka State Agricultural Academy, Kirov.
   
Abstract: In the article there are some facts about the behavior and medical effectiveness of the ozonired emulsion in post natal stage by acute endometritis cows. The offered method in the therapy by cows suffering from acute endometritis makes the medical activities more effective and decreases the period from calving to fertilization.
   
Keywords: endometritis, therapy, cows
   
   
   
Title:

PROTECTIVE SYSTEMS CALVES WITH WASTING SYNDROME AND THEIR ROLE IN THE DEVELOPMENT OF NEONATAL PATHOLOGY

   
Authors: Shakhov A.G.; Fedosov D.V.; Sashnina L.Yu.; Mas’yanov Yu.N.; Erina T.A.; Alyokhin Yu.N.
   
Address: All-Russian Veterinary Pathology Pharmacology and Therapy Research Institute.
   
Abstract: Violation of fetal exposure is the main cause of the weakening of adaptive mechanisms in the newborn, along with other contributing factors of neonatal disease in calves. Before the appearance of clinical signs of gastrointestinal disease is accompanied by a marked reduction maladjustment calves with wasting syndrome natural resistance and the imbalance between the key mediators produced by various cell types, in addition to providing the adhesion molecules, intercellular communication and remote response to the introduction of foreign agents, immune damage, inflammation and regenerative processes in the body.
   
Keywords: calves, neonatal pathology, cytokines, gastrointestinal disease
   
  Zootechny
   
Title:

MEN'S TEAM MATES AT THE TATARSTAN TYPE CATTLE AND THEIR GENETIC POTENTIAL

   
Authors: Afanasiev A.P.; Haeretdinov R.R.; Khazipov N.N.
   
Address: The Kazan State Academy of Veterinary Medicine named after Bauman N.E.
   
Abstract: In order to improve the type of livestock until the, tatartype  category of, SA-breed within the type formed men's team-mates by potential future breed lines. Set their genetic potential productivity. Identify the most productive group of Leo 857, kinship connection, 21, 25 and other Wind with a development perspective in the breed, which provides annual breeding effect on 1 + 101 kg milk cow and +0.01% body fat.
   
Keywords: genetic potential,index of ancestry, related group, supported, tatar type, bull
   
   
   
Title:

GROWTH, DEVELOPMENT, SAFETY AND EFFICIENCY OF YOUNG PIGS AT APPLICATION BY THE PROBIOTIC COW OF THE ADDITIVE OF PROLAM

   
Authors: Alekseev I.A.; Vengrenyuk D.G.
   
Address: Chuvash State Agricultural Academy.
   
Abstract: Development of branch of pig-breeding is impossible without cultivation of healthy young growth. In modern conditions the increase in mass incidence and a case of animals cause big economic damage. Use of antibiotics for treatment and prevention of diseases of animals involves development of resistant microflora and negatively affects on health of animals. Now for the solution of this problem a probiotics and the pro-biotic feed additives representing autoimmune for an intestinal biocenosis of animals strains of bacteria is actively used. Prolam treats such preparations.
Use of probiotic feed additive Prolam at cultivation of young growth of pigs till 30 days of life (with a week interval) on 4 ml, and from the 30th to the 120th day (with a week break) - on 6 ml counting on one head, promotes their best growth, development, safety increase by 8,00% (Ð<0,01) and an average daily gain of live weight for 8,08% (Ð<0,01). Influence on physiological indicators of an organism of pigs isn't revealed.
   
Keywords: a probiotic fodder additive of Prolam, young growth of pigs, live weight, a gain, safety, efficiency
   
   
   
Title:

DATA OF THE QUALITY OF MEAT IN THE APPLICATION SHUNGITE

   
Authors: Tremasova A.M.; Korosteleva V.P.
   
Address: Federal Center of Toxicological, Radiation and Biological Safety, Kazan.
   
Abstract: The main objective is to provide a modern livestock environmentally friendly livestock production. Any animal diseases, and the use of preventive and therapeutic agents from the quality of the manufactured products, causing significant damage to the industry. An important aspect in the application of treatment and prevention of animal diseases is their influence on animal health indicators of the finished product, particularly meat.
Purpose of the study was to estimate the sanitary veterinary meat pigs after application as a prevention of shungite.
Organoleptic study showed that the meat of pigs as experimental and control groups meets fresh, good-quality meat.
Visual inspection pig meat was pale pink, fat, soft, white, flexible. The degree of bleeding is good, with cut muscle blood spots are allocated. On the surface of the meat is covered with a crust of rustling drying. Consistency elastic, fossa of finger pressure equalized quickly. The smell is typical for this type of animal meat.
Sample boiling showed that broth obtained from meat of experimental and control animals comply with the limits for fresh meat benign: fragrant, clear, with drops of oil on the surface.
When the physicochemical study found that meat from animals of both groups should be similar to one from the other and meets the standards prescribed for benign fresh meat.
The results suggest a positive effect on health shungite meat quality of pigs. Meat experimental animals in the organoleptic, physical and chemical parameters can be regarded as a benign.
   
Keywords: pork, shunpike, veterinary and sanitary assessment, quality
   
  Radiobiology
   
Title:

MORPHOLOGICAL PICTURE OF PARENCHYMAL ORGANS OF THE WHITE RATS RECEIVING FOOD, SUBJECTED TO BEAM TREATMENT

   
Authors: 1 Malushko A.V., 2 Konjukhov G.V., 1 Velikanov V.I., 1 Parkina M.A., 2 Kurbangaleev Y.M., 2Shigapova G.Z.
   
Address: 1. Federal State Educational Establishment High Professional Education Nizhny Novgorod State Agricultural Academy, Nizhny Novgorod.
2. Federal Center of Toxicological, Radiation and Biological Safety, Kazan.
   
Abstract: One of the tasks of modern agricultural development is the introduction of new technologies for environmentally safe products. In this respect, the introduction of radiation technologies require careful consideration of their safety.
Studies discovered that prolonged for 6 months the feeding of white rats subjected to radiation oats treatment at a dose of 300 G, does not cause significant changes of morphological parameters of parenchymatous organs.
   
Keywords: radiating technologies, safety, food
   
  Physiology
   
Title:

EFFECT OF LEUKOCYTES SUBPOPULATIONS FOR ELUTION OF TRANSAMINASES BY LIVER CELLS OF WHITE MICE

   
Authors: Malinin M.L., Gabalov K.P., Laskavy V.N.
   
Address: State Institution Saratov Scientific and Recearch Veterinary Institute Russian Academy for Agricultural Sciences, Russia.
   
Abstract: Studies were conducted on peritoneal cells, separated the cells of the liver, spleen and blood of white mice. Shown that both AST and ALT released of the cells of the liver, and the activity of enzymes depends on the content in the environment of different leukocyte subpopulations. It is shown that AST has on the immune response involved in the white cells activating effect, which is reflected in the increase in the intensity of cellular respiration. The effect was most pronounced for the cells, less pronounced for peritoneal macrophages and neutrophilic granulocytes for small series. These results suggest that the liver cells involved in the immune response, perceiving information on quantitative and qualitative characteristics of the white blood cells and correcting the metabolic activity of leukocytes through the allocation Wednesday enzymes, especially enzymes AST and ALT.
   
Keywords: liver, leukocyte subpopulations, enzymes
   
   
   
Title:

THE USE OF QUANTUM RADIATION FOR HEMATOLOGIC INDICES CORRECTION IN ANIMALS

   
Authors: Kalyazina N.Y.; Zenkin A.S.
   
Address: Mordovian Ogarev State University, Saransk, Russia.
   
Abstract: The experimental animals were female rabbits aged 1 year weighing 3 kg. Zone for the local effects of laser infrared radiation are selected based on the highest concentrations of biologically active points, responsible for blood, ie on the left side of the blade. Place shear effects, shaved and degreased 96o alcohol to make direct contact with the skin of animal heads. Worked on the selected zone contact method, using a special attachment for this quantum therapy device for veterinary practice "RIKTA-01" (M2V), 50 Hz, for 3 minutes. In the whole blood of experimental animals studied red blood cells, white blood cells, lymphocytes, neutrophils, and force leukogram.
After the local impact of laser radiation in the infrared points BAT rabbits noted the following changes in the peripheral blood leukocyte count increased on day 3 is due primarily due to higher levels of lymphocytes, also on day 3 was a sharp increase in the number of red blood cells and the lack of young forms of neutrophils . Other indicators are behaving quite stable. Obtained in the course of the experiment data suggest synergistic effects when exposed to quantum radiation on acupressure points that are responsible for blood formation, occurring in vivo and confirmed hematologic studies.
   
Keywords: quantum radiation, blood, rabbits, synergy
   
   
   
Title:

DYNAMICS OF GROWTH, IMMUNOLOGICAL AND METABOLIC PROCESSES AT BULL-CALVES IN THE CONDITIONS OF THE APPLICATION OF NEW BIOGENIC COMPOUNDS

   
Authors: Yakovlev G.A.; Shukanov A.A.
   
Address: Chuvash State Pedagogical University named after I.Yakovlev, Cheboksary.
   
Abstract: To ensure proper protection of the health of animals are required to comply with the new principle - environmental-adaptive, based on the use of antioxidants, immunotropic funds, adaptogens, vitamins, micro-and macro-elements, etc., characterized by high of prevention and treatment efficiency and environmental harmless for the organism.
The objective is to assess the corrective effect of biopreparations «Sedimin-Se +» and «Trepel» on a clinical and physiological condition, the body growth, natural resistance and a metabolism at bull-calves in age aspect.
One series of scientific and economic experiences and laboratory experiments is carried out. 1 groups (control) contained animals on the main diet (MD). To bull-calves of 2 groups against the main diet daily fed «Trepel» in a dose of 1,25 g/kg of weight of a body since 90-day age and until the end of experiences; animal of 3 groups in 1, 25 and 50th day of life intramuscularly entered an organic antioxidant «Sedimin-Se +» in a dose on 0,1 mg/kg of weight of a body and in addition fed «Trepel» according to the scheme stated above.
Physiological expediency of appointment is experimentally proved to bull-calves of biological preparations «Sedimin-Se +» and «Trepel» which possess rather wide range of positive biological effects on an organism.
So, at 120-, 360-and 540-day experimental bull-calves at the end of the periods of breeding,, rearing and fattening the mass of body weight, the number of erythrocytes, leukocytes, hemoglobin level, ABOK, peroxidase in the blood; the content of total protein, albumin, ?-globulins, immunoglobulins, the amount of acid capacity in the blood serum were higher by 2.9-45,6% (P<0.05-0.001), and the concentration of alkaline phosphatase activity, lipid peroxidation and the antioxidant system, on the contrary, lower by 16.6-47,6% (P<0.05-0.001)than they are in control.
   
Keywords: oxen, immunogenesis, metabolism, «Sedimin-Se+», «Trepel»
   
   
   
Title:

FOOD ADDITIVES OF BATSELL, LARICARVITAS AND THEIR INFLUENCE ON THE ALBUMIN EXHANGE AND LAMB PRODUCTIVITY

   
Authors: 1Pavlova M.V.; 1Alekseyev I.A.; 2Sofronov V.G.
   
Address: 1. The Chuvash State Agricultural Academy.
2. The Kazan State Academy of Veterinary Medicine named after Bauman N.E.
   
Abstract: «Batsell» and «Laricavitas» have high effectiveness in the profilaxis of gastro-intestinal diseases. The first includes microbe mass of spore forming bacteria Bacillus subtilis acidophilous bacteria Lactobacillus acidophilus, Ruminococcus albus, which promote digestion improvement and bacteriosis prophylaxis. The first contains chlorophyll, beta – carotene, larch complex. The indicated food additives process expressed biological activity, strengthen immune system, favour growth, development and lamb safety.
The results of the indicated food additive influence on the young lamb organism is shown in this work. It is established, that the introduction of these food additives into the main ration render positivety on the morphological and albumin status in the lamb organism. So, application of probiotic additive to the forage «Batsell» during 10-30 days per 5,0 g, after 30 days per 10 g. and vitamin content carotene-chlorophyll food additive «Laricarvitas» 10 g. per 1 kg of body mass once for twenty-four hours during 120 days favored the raise of erythrocytes to 5,70 and 5,33% (P<0,05), hemoglobin - to 6,17 and 6,06% (P<0,01), the raise of albumin in the blood whey to 7,93 and 7,81% (P<0,01), albumin - to 7,52 and 7,77% (P<0,01), globulin – for 12,27 and 12,01% (P<0,01), average daily growth of live mass to 9,89-9,34% (P<0,01) end young lamb safety to 3,5 – 4,0% (P<0,05).
   
Keywords: probiotic additive of Batsell, carotine - chlorofill food additive, influence the mechanism on the animal organism, basic morphological blood indicators, common protein, albumin, globulin, gamma - globulin, young lamb body mass growth