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╣ 6, 2012

  Toxicology
   
Title:

ABOUT A CAUSE OF FISH KILL IN THE WATER OBJECTS OF THE REPUBLIC OF TATARSTAN

   
Authors: Makaeva V.I., Akhmetzyanova G.F., Makaeva A.R.
   
Address: Federal Center of Toxicological, Radiating and Biological Safety, Kazan.
   
Abstract: The possible causes of fish kill in the water objects of the Republic of Tatarstan have been analyzed. Investigations of water samples selected from the water objects of the Republic have been carried out and results of ones are presented. An excess of nitrites, ammonium, phosphates, suspended solids and reduced levels of dissolved oxygen are found. Water samples had organoleptic deviations. It is found, that the main cause of mass fish kill in the water objects is the discharge of waste water containing large quantities of organic pollutants of different etiologies. Therefore, it is necessary to supervise the operation of the purification plants and discharge of waste water at different levels as the preventive measures of water pollution and, as a consequence, conservation of aquatic biodiversity.
   
Keywords: water, pollution, water quality standard, dissolved oxygen, fishes
   
   
   
Title:

PECULIARITES OF COMBINED MICROELEMENTS SORPTION BY VARIOUS SORBENTS

   
Authors: Biktashev R.U., Papunidy K.H., Yermakova E.I., Portkov O.V.
   
Address: Federal Center of Toxicological Radiation and Biological Safety, Kazan.
   
Abstract: Represented results of research of combined microelements sorption by enterosorbents in vitro and in vivo with varied concentrations. The dose 1% of sorbents bentonite, modified bentonite, toxfin, ecofiltrum, mycosorb was studied in rat diets. Toxfin and ecofiltrum posseess the most sorption of iron. Zinc is actively adsorbed by toxfin, mycosorb and ecofiltrum. Adsorbtion of cooper in the digestive tract of animals is insignificant, such a picture is characteristic for manganese. Cobalt is more actively sorbed by bentonite (27,2 ľ 35,7), ecofiltrum (16,6 ľ 23,2%), mycosorb (10,6 ľ 28,6%). Receipt data can be used for correction of mineral premixes in process of long preventional using of studied sorbents.
   
Keywords: microelements, sorbents, adsorption
   
   
   
Title:

THE INFLUENCE OF THE COMBINATIONS OF MONOMETHYL ESTER CETOTETRACARBOXYLIC ACID WITH ANILOCAINUM AND POLIFLOXACIN (OmeCTCA + └NILOCAINUM + POLIFLOXACIN) ON THE COURSE OF FREE RADICAL OXIDATION LIPIDS

   
Authors: Ismagilova A.F.; Chudov I.V.
   
Address: Bashkir State Agrarian University, Ufa, Russia.
   
Abstract: In the development of new drugs special attention is given to tests to determine the likelihood of their cytotoxicity effects. An important indicator of this process is the change of the mechanisms of normal tissue cell structures that maintain the balance of the antioxidant defense system.
In article experimentally well-founded material opening aspects of pharmacological efficiency of new combinations OmeCTCA+└nilocainum+Polifloxacin (1:2:0,2). It is proved that the appointment of a seven-day combinations of OmeCTCA+└nilocainum+Polifloxacin (1:2:0,2) at a dose of 25 mg/kg is not capable of inducing cytotoxicity in organs and tissues of animals, opposite improving the quality of the streaming of lipid peroxidation and preventing free-radical oxidation processes.
Use of the combinations OmeCTCA+└nilocainum+Polifloxacin (1:2:0,2) in a dose of 25 mg/kg for seven days, increases the concentration of glutationperocsidasis in red blood cells of the experimental group of rabbits to 18,51▒0,29 mkmol/ml/min (on 24,73% over the original value (14,84▒0,42 mkmol/ml/min) and on 40,12% increase compared to the value of this index in the control group (13,21▒0,11 mkmol/ml/min). Catalasis activity in the blood of rabbits of the experimental group increased to 37,03▒0,28 mmol H2O2/l, whereas in the red blood cells of rabbits of the control group it was only 34,57▒0,28 mmol H2O2/l, which is 6,64% lower than the values being compared. In conducting research also suggested improving the exchange of fat-soluble vitamins in the body of rabbits. Tocopherol and retinol concentration in the serum of rabbits treated with the combinations of OmeCTCA+└nilocainum+Polifloxacin (1:2:0,2) in a dose of 25 mg/kg increased from 1,88▒0,02 mkg/ml to 2,24▒0,02 mkg/ml and from 0,23▒0,01 mkg/ml to 0,43▒0,02 mkg/ml, respectively.
The research results give reason to use the OmeCTCA+└nilocainum+Polifloxacin (1:2:0,2) combinations in pathologies characterized by hypoxic events, as well as endogenous and exogenous intoxication with symptoms cytolisis characters.
   
Keywords: pharmacology, toxicology, triterpenoids, free radical oxidation of lipids, antioxidant systems
   
   
   
Title:

VETERINARY-SANITARY EXAMINATION OF MEAT OF CALVES IN THE COMBINED POISONING PYRETHROIDS, MYCOTOXINS AND HEAVY METALS

   
Authors: 1Papunidi E.K., 2Korostyleva L.P., 3Egorov V.I.
   
Address: 1. Kazan State Academy of Veterinary Medicine.
2. Kazan Cooperative Institute.
3. Federal Center of Toxicological, Radiation and Biological Safety, Kazan.
   
Abstract: This article presents the results of research on animal health examination and evaluation of meat merchandising calves with combination of pyrethroid, mycotoxins and heavy metal.
   
Keywords: pyrethroids, micotoxins, heavy metals, veterinary-sanitary examination
   
   
   
Title:

TOXIC PROPERTIES OF BIOSTIMULATING PREPARATIONS PS-6 AND PS-7

   
Authors: Nikitin D.A.; Semenov V.G.
   
Address: Chuvash State Agricultural Academy.
   
Abstract: The staff of the Chuvash state agricultural academy developed immunomodulators PS-6 and PS-7. These preparations possess a number of advantages, complex immunostimulating, antibacterial and antiviral action is basic of which.
For the purpose of test of safety of preparations their average lethal doses were defined, and the toxic influence caused by their overdose is estimated. Calculation of an average lethal dose carried out on rats by means of mathematical processing on Kerber's formula. At an assessment of the toxic influence caused by overdose, for a basis took recommended therapeutic and average lethal doses of preparations.
Average lethal doses of preparations PS-6 and PS-7 made 2,55 and 2,30 ml on 1 kg of live weight.
Preparations don't render expressed toxic impact on an organism of laboratory animals at single introduction in a dose in 6 times exceeding the therapeutic. At overdose in 9 and more times are capable to have the toxic influence which is expressing in decrease in impellent activity, lack of appetite, violation of structure of an integument in the form of allopetsiya and gemorragiya. These phenomena are reversible and don't cause the expressed complications and pathologies in an organism of animals.
Thus, results of researches on determination of toxic properties of preparations PS-6 and PS-7 testify to width of therapeutic action of studied immunomodulators.
   
Keywords: toxicity, average lethal dose, immunomodulator, PS-6, PS-7
   
   
   
Title:

THE USE OF NEW SORBENTS FOR REARING PIGS

   
Authors: 1Tremasova A.M., 1Burdov L.G., 1Bielecki S.O., 2Mitrohin M.Yu.
   
Address: 1. Federal Center of Toxicological, Radiation and Biological Safety, Kazan.
2. LLC źBiopreparation╗.
   
Abstract: One of the main tasks of the modern animal is to obtain environmentally friendly products. Any animal disease to the safety and productivity of livestock, as well as the products obtained, causing significant damage to the industry.
The use of sorbents polisorbin, shungite and bentonite had a positive impact on the dynamics of live weight of pigs of all experimental groups. Average daily gain in the experimental groups was 516, 483 and 472 g, and in control - the consumption of 427g of approximately equal amounts feed. In the experiment, the animals of all experimental groups was an increase in the number of red blood cells and hemoglobin in the first group - at 3.6 and 5.17% in the animals of the second and third groups - 2.99, 6.27 and 2.89; 6.12%, respectively. In the control group, these figures have not changed significantly and were at the lower limit of normal.
White blood cell count, is initially at the upper limit rules in all the experimental groups decreased. The control group also was an increase in this indicator is 15.4% of the outcome.
In the blood of the animals of the experimental group, an increase in total protein content in relation to the background values of 3.8, 4.2 and 4.8%, respectively, in the control group, the figure stood at the baseline level. Phagocytic activity on the 30th day of the study in the first experimental group increased by 6.6% in the second - by 5.9% and in the third - by 6.1% relative to the background. Phagocytic number increased relative to the background values in the first group - 16.9%, in the second - by 16.2%, in the third - by 16.4%. sorbents help to increase the weight of the animals and increase the body's resistance to adverse environmental factors.
   
Keywords: sorbent, pig, poisoning, mycotoxicosis, prevention, treatment
   
  Infectious pathology
   
Title:

PECULIARITY OF HEAT SHOCK PROTEIN (HSP70) IMPACT ON IMMUNË RESPONSE TO INACTIVATED WHOLE-PARTICLE AND SPLIT VACCINES AGAINST TICK-BORNE ENCEPHALITIS

   
Authors: 1Vargin V.V.; 2Sapojnikov A.M.; 1Ljapustin V.N.; 1Zylkova M.V.; 1Belyakova A.V.
   
Address: 1. Chumakov M.P. Institute of Poliomyelitis and Viral Encephalitis, Russian Academy of Medical Sciences.
2. Shemyakin M.M. and Ovchinnikov Yu.A. Institutes of Bioorganic Chemistry, Russian Academy of Sciences.
   
Abstract: Distinct HSP70 impact on humoral and cell immunity to the whole virus particle and split vaccine against TBE virus has been found. This difference involves predominantly humoral branch of immunity and is putatively caused by different physical and chemical properties of the antigens.
   
Keywords: heat shock protein, vaccines, stimulation immunity, tick-borne encephalitis
   
   
   
Title:

STUDY OF INFLUENCE OF XIMEDONE ON IMMUNITY OF NEWLY-BORN CALVES

   
Authors: 1Setdekov R.A., 2Yusupov R.H., 2Sadykov N.S.; 2Makaev Ch.N.
   
Address: 1. State Veterinary Administration of Krasnooctyabrsky district, Nizhny Novgorod.
2. źFederal Center of Toxicological, Radiation and Biological Safety╗.
3. All-Russian Research Institute of Experimental Veterinare named after Kovalenko.
   
Abstract: The newly-born calves with signs of dyspepsia are determined to have reduced parameters of natural resistence. Such animals have reduced level of general leucocytes and IgG, IgM lysozymic activity comparing to physiological norm. Bouble introduction of ximedone in 30 ml/kg ratio improves the recovering of the investigated parameters. Along with it the drug largely increases bactericidal and lysocymic activity, phagocytes activity of leucocytes, as well as whole protein and its fractions, number of t- and B-lymphocytes that indicates that ximedone promotes biological and immunological respond of organism.  
   
Keywords: calves, newly-born calves diseases, immunological parameters, ximedone
   
   
   
Title:

REFERENCE PREPARATION TO CONTROL THE IMMONOGENICITY OF VACCINES AGAINST RABIES OF ANIMALS

   
Authors: 1Puchova N.M.; 1Samuylenko A.Ya.; 2Elakov A.L.
   
Address: 1. źAll-Russia research and institute of technology of the biological industry╗ (Shelkovo).
2. źVirology research institute of D.I.Ivanovsky╗ (Moscow).
   
Abstract: The national branch standard (referens-vaccine) was developed for standardization of control methods of an immunogenicity of vaccines against  rabies of animals and reduction of indicators received thus to a uniform international denominator. Comparative tests showed full compliance of a domestic preparation with the 5th international standard. Immunogenic activity, otkalibrovanny on the international standard, makes 1,8 ME/ml. The reference preparation is stored at temperature 20Đ that provides activity maintenance at constant level almost unlimited time. Now application of a referens-vaccine is obligatory at control of an immunogenicity of inactivate rabies vaccines by a volume method of National institutes of Health USA (NIH).
   
Keywords: rabies, referens-vaccine, immunogenicity
   
   
   
Title:

MONITORING OF RABIES VACCINOPROPHYLAXIS OF WILDLIFE IN KALININGRAD REGION, RUSSIA

   
Authors: 1Khismatullina N.A., 1Petrova T.P., 1Gulyukin A.M., 1Sabirova V.V., 1Gafarova A.Z., 1Nasyrov Sh.M., 1Markova M.I., 2Yelakov A.L.
   
Address: 1. Federal State ľFinanced Institution źFederal Center for Toxicological, Radiation, and Biological Safety╗.
2. Virology Research Institute named after Ivanovsky D.I. (Moscow).
   
Abstract: Oral vaccination of wild carnivores in the Kaliningrad region is held annually since 2007, using national anti-rabies vaccine "Oralrabivak" based on the "RB-97" strain produced by "Pokrovsky plant of biological products" JSC. The vaccine is spread using the Sintal-2 aircraft. In 2007-2009 vaccination was carried out only once, and since 2010 twice a year ľ in spring and autumn. We investigated 500 brain samples, blood serum and foxes and raccoon dogs shoot in the vaccinated region during 2011 and 2012. The efficiency analyses of wildlife carnival animals oral vaccination in Kaliningrad region demonstrated reduction of sickness rate in 2011 (21 cases) comparing to 2006 (46 cases) for 2.2 times; bait intake by foxes was 67,2% and serum conversion rate was 67.1%; bait intake by raccoon dogs was 58.8% and serum conversion rate was 44,0%. We recommend to vaccinate wildlife carnivals orally along with regulation of population density within 0,1-0,2 foxes per 1 km2 in the overpopulated regions.
   
Keywords: rabies, vaccinoprophylaxis, bait intake rate, serum conversion rate
   
   
   
Title:

EPISOOTIC PARTICULARITIES OF FORMING OF NOZOPROFILE OF INFECTIOUS AND INVASIVE PATHOLOGY IN NIZHNIY NOVGOROD AREA CONDITIONS

   
Authors: 1Shilkina L.V.; 1Kozyrenko O.V.; 2Kolobov E.A.; 1Piuncina V.V.; 3Pomazov E.A.; 3Jezlova N.V.; 1Aliev A.A.; 1Petrushkina E.S; 1Sochnev V.V.
   
Address: 1. Federal State Educational Establishment High Professional Education Nizhniy Novgorod State Agricultural Academy.
2. Committee of state veterinary control of Nizhniy Novgorod region.
3. Management of veterinary medicine of Nizhniy Novgorod.
   
Abstract: In comparative aspect and in dynamics we researched the infectious and invasive pathology in poultries in Nizhniy Novgorod area and in other areas, and also in Russian Federation in the whole. We researched the some epizootic parameters of population of birds; total pathology of poultries and its main causes was also researched.
   
Keywords: parasites, nematodosis, synergism, antagonism, mono- and mixinvasions
   
  Non-transmittable diseases
   
Title:

INFLUENCE OF PROBIOTIKA ON PHYSIOLOGY OF CEKAL'NOGO OF DIGESTION OF RABBIT AT INCREASE OF STAKE OF NITROUS COMPONENTS IN RATION

   
Authors: Laktionov K.S.; Kozlov A.S.; Buyarov V.S.
   
Address: Orel State Agrarian University (Orel).
   
Abstract: Introduction of intensive technologies changed character of feed base not only in number but also high-quality, pulling out the problem of creation of forage additions which besides a nourishing value affect overcooking of feed or his absorption directly in fabrics of digestive highway, stimulate the secretion of digestive enzymes, and also growth and development of rabbit. One of important functions of microbiocenosis of gastroenteric highway is participating  in the processes of digestion. The features of microbal simbiontnoy fermentation depend on the type of feeding of zoon, amount of consumable feed, correlation in him of nutritives and related to the specific of structure of digestive highway, physiology of zoon, and also with specific composition and fermentativnoy activity of mikrosimbiontov departments of ZHKT, in which favourable terms are created for their development. An experiment showed the positive affecting  of probiotika physiology of cekal'nogo digestion of rabbit at the increase of stake of nitrous components in a ration. Application of investigational additions is expedient in the industrial rabbit breeding.
   
Keywords: probiotiki, digestion for rabbit, perevarimost' of nutritives, living mass
   
   
   
Title:

IMMUNOTROPIC THERAPY IN THE PREVENTION OF COW MASTITIS: IMPACT ON PRODUCTIVITY AND QUALITY OF MILK

   
Authors: Vorobyev A.V.; Sadov K.M.
   
Address: Samara Research Veterinary Station Russian Academy for Agricultural Sciences.
   
Abstract: The aim of the present work was to study the effect of experimental bacteria-derived immunostimulant on the cow milk yield and quality. The study was performed using "Klever" and "Somatos-M" milk analyzers.
The results demonstrasted that the immunostimulant contributes in reduction of somatic cells in bulk milk. In the treatment group within the observation period the average amount of cells was less than 200▒15.2 cells while in controls the said marker made up 485▒8.2 cells. The immunostimulant promoted to increase of fat and protein in bulk milk by 1.2 and 10.2%, respectively.
The experimental immunostimulant contributed in 3.18-fold reduction of subclinical mastitis and also decreased the rate of clinical mastitis by 55.2%.
   
Keywords: immunostimulator, cows, mastitis, milk, quality, somatic cells
   
  Parasitology
   
Title:

SPREADING OF HELMINTHIASIS IN DOMESTIC CARNIVOROUS IN CHUVASH REPUBLIC

   
Authors: Kosyaev N.I., Farkhutdinova A.F.
   
Address: Chuvash State Agricultural Academy.
   
Abstract: Helminthofauna of domestic carnivorous and spreading of helminthes in Chuvash Republic had been investigated. 13 species of domestic carnivorousĺ helminthes had been discovered. 
   
Keywords: helminthofauna, cats, dogs, contamination, helminthĺs eggs
   
   
   
Title:

DIAGNOSTICS OF TOXOCAROSIS

   
Authors: 1Dolbin D.A.; 2Idrisov A.M.; Lutfullin M.Sh.; 2Mingaleev D.N.
   
Address: 1. Kazan Institute to Epydemiology and microbiology Rospotrebnadzora
2. Kazan State Academy of Veterinary Medicine named after Bauman N.E.

   
Abstract: Steel alive diagnosis of human toxocarosis is practically impossible because of migrating character of larvaes. Leading method of diagnosis is immune diagnosis.
In adding to this method is suggested specific IgE method, revealing antigen and circulating antigens of spp. Toxocara in serum. The dynamic of this indicators can serve as an criterion for the effectiveness of specific therapy.
First of all the differential diagnosis is splendid with early forms of helmintiasis, such as ascariasis, strongyloidiasis, shistosomiasis, opistorchiasis.
Essencial moment in diagnosis of Toxocara is present  epidemic history of disease.
In this connection was developed more efficient way of diagnosis. It is coproscopy method of diagnosis of helmyntosis of carnivores.
It must reveal helmintological situation to appropriate treatment and preventive measures in the study of  sites.
As a result, new method has revealed   about 100% invasion of tested animals. In addition, our method is effective in revealing unfertilized eggs Toxoascaris leonine. Method of Fyulleborn is much less effective.
The developed method of diagnosis of helminth invation in carnivores is much more effective to compare with method of Fyulleborn.
As a result of helmyntoovoscope achievements, on practice have been dogs dewormed.
   
Keywords: diagnostics toxocarosis, gelmyntoovoscopy the combined method
   
   
   
Title:

PATHOMORPHOLODICAL CHANGES BY BABESIOSIS CATTLS

   
Authors: Vasilevich F.I.; Madiarov T.T.
   
Address: Moscow State Academy of Veterinary Medicine and Biotechnology by K.I. Skryabin.
   
Abstract: Researched pathologo-anatomical picture babesiosis in cattle, which characteristic icterus, anemia, degeneretiv change internal organs and splenonmegalia.
   
Keywords: cattle, babesiosis, icterus, anemia,splenomengalia, liver, nephris
   
  Zootechny
   
Title:

THE USE OF MARKER ASSISTED SELECTION IN DAIRY CATTLE BREEDING

   
Authors: Shakirov S.K.; Ulmeteva Y.R.; Zinnatova F.F.
   
Address: The Tatar research Institute for └griculture of Russian └gricultural Academy, Kazan.
   
Abstract: One of the main conditions to increase milk production and improve the efficiency of dairy cattle in our country is the qualitative improvement of the breed and the genetic potential of increasing productivity. At present, this can be achieved in addition to classical breeding, molecular breeding techniques, which today can identify animals with increased production and processing properties. By the authors  testing of the bulls-manufacture on genes-markers of milk production, such as the CSN3, PRL, DGAT1, LGB. Research has established that the desired genotype at CSN3BB had 6% of the total population, the gene PRL┬┬ only one animal - 1% for the gene butterfat DGAT1╩╩ 4%, 44% gene LGB┬┬. This report stresses the need for a selection marker, to identify animals with desirable genotypes on the marked genes, markers, to improve dairy cattle productivity and improve the quality of the milk.
In order to control the genetic diversity of dairy cattle breeding in leading the RT and effective use in the selection process, it is recommended to carry out the molecular genetic testing of dairy cattle on genes CSN3, PRL, DGAT1, and others for an objective assessment of the situation and genetic accumulation in herds of desirable complex genotypes that increase milk production and improve the quality of milk cows.
   
Keywords: PCR, marker-assisted breeding, genetics, gene, cattle
   
   
   
Title:

GROWTH AND DEVELOPMENT OF CALFS IN USING PROBIOTIC ADDITIVE źBATSELL╗ TO THE F0RAGE

   
Authors: Alekseyev I.A.; Petrova S.G.
   
Address: The Chuvash State Agricultural Academy.
   
Abstract: In application of this fodder additive there was seen anthentic increase of erithrocytes on 5,86 (đ<0,05), leukocytes on 3,38 (đ<0,05), hemoglobin for 6,82% (đ<0,01) in the blood of experimental animals in comparison with control analogs, within physiological norm. Indroduction of this fodder additive in the main diet of the calves promoted insignificant growth of endocellular enzymes of reamination-nuclear heating plant aspartataminetransferasa and a alaninaminetrancferasa in  serum of blood  and activization of an albuminous exchange in an organism of experimental animals. It is  proved by increase of the specified enzymes on  0,02 ľ 0,03 mmols,  level of the general protein on 6,89 (P<0,01), albumin - on 3,68 (đ<0,01), globulins - on 6,34 (đ<0,01), gamma - globulins - on 20,43 % (đ<0,001) serum of blood, of the calves. So, at 60-dayly age the height in crest of experimental calves was higher on 1,12 cm, the slanting length of the body on 0,78 cm, a breast grasp behind shovel on 0,94 cm, a grasp of shang on 0,92 cm, than at control contemporaries or it is more than 4,65-5,32 % (đ<0,05). According to the application of the  tested fodder additive  we cab see an increase of a dayly average gross for 7,56%, natural resistance  on 7,44%, and safeties on 6,65 % in experimental calves.
   
Keywords: probiotic additive of Baesell undergrowth, horned cattle, daily, average, gain, live weight
   
  Radiobiology
   
Title:

TO A PROBLEM OF SEARCH OF PROTECTION FRAMES AT DEFEAT OF ANIMALS BY THE IONIZING RADIATION

   
Authors: Konjukhov G.V.; Gareev R.D.; Aslanov R.M.; Tarasova N.B.; Velikanov V.I.; Sychev K.V.
   
Address: 1. Federal Center of Toxicological, Radiating and Biological Safety, Kazan.
2.  Federal State Educational Establishment High Professional Education Nizhny Novgorod State Agricultural Academy, Nizhny Novgorod.
   
Abstract: Experiments on studying of preventive efficiency of a chemical preparation and fabric antigenes are spent on laboratory (white mice, white rats) and agricultural (sheep) of animals.
It is established, that the greatest radio protective activity preparation ď-3 (sulfotozifan) possesses. At unitary hypodermic introduction to white mice of a preparation ˝ˇŰآţ˛ţšŔ˘ÓÝ in a dose of live weight of 34 mg/kg for 2-4 days before external gamma irradiation in an is absolute-deadly dose are protected accordingly by 20, 60 and 80% of animals.
One of the early and expressed reactions of an organism on an irradiation was change of number of cages of white blood. On all extent of experiment at the irradiated rats that entered sulfotozifan and fabric preparations, reduction of quantity of leukocytes was observed, however at protected animals in all terms of experience it was above. Within the first days after an irradiation of change of quantity erythrocytes and concentration of haemoglobin were insignificant, during the period with 21 days changes from red blood had more expressed character. At the irradiated rats receiving sulfotozifan and fabric preparations, maintenance MDA in blood plasma was lower, than at not protected animals. The minimum of quantity of T-cages at animals of the given group is noted on 14 days - 13,8% (50% from level of the biological control). The minimum of quantity B-lymphocytes at animal skilled groups is noted on 7-14 days. After this with 21 days after an irradiation there is a restoration of V-cages on 22-55%.
Described in the literature and the property of some chemical compounds confirmed with us and fabric preparations to raise survival rate of animals at ionizing radiation influence allows to use them in a complex of actions protection.
   
Keywords: a radiation injury, preventive maintenance, fabric antigens, sulfotozifan, efficiency
   
   
   
Title:

MORPHOLOGICAL AND BIOCHEMICAL INDICATORS OF BLOOD OF THE WHITE RATS RECEIVING FOOD, SUBJECTED TO BEAM TREATMENT

   
Authors: 1Malushko A.V., 2Konjukhov G.V., 1Velikanov V.I., 1Parkina M.A., 2Kurbangaleev Y.M.
   
Address: 1. Federal State Educational Establishment High Professional Education Nizhny Novgorod State Agricultural Academy, Nizhny Novgorod.
2. Federal Center of Toxicological, Radiation and Biological Safety, Kazan.
   
Abstract: Long within 6 months ˝ŕÓ­ýŰŔÔÓÝŔň in a diet of white rats of forages subjected to beam gamma processing in a dose 300 Gr does not cause authentic changes of morphological and biochemical indicators of blood in comparison with that of control animals.
   
Keywords: radiating technologies, food, safety
   
  Physiology
   
Title:

CYTOLOGICAL CHARACTERISTICS OF THE CHANGE OF THE RED BONE MARROW IN APPLYING CSF

   
Authors: Zenkin A. S.; Kalyazina N. Y.
   
Address: Mordovian Ogarev State University, Saransk, Russia.
   
Abstract: The aim of research was to evaluate the changes of bone marrow cell count rabbits when administered to them the cerebrospinal fluid of cattle in the area of biologically active points, responsible for blood.
The studies were conducted in rabbits, 1 year old, live weight of about 3 kg of healthy, of which formed the control and experimental groups of 10 animals each. The animals were taken before the experiment blood and bone marrow for testing. Feeding and animal control and experimental groups was the same.
Within a month, watching the clinical condition of the animals in both groups and were selected for the study of blood and bone marrow at 3, 10 and 30 days after the statement of experience. In the whole blood of experimental animals studied red blood cells, white blood cells, lymphocytes, and neutrophils. In bone marrow determined the number of nucleated cells and deduced myelogram.
Based on these results, the following conclusions: after application of cerebrospinal fluid in the area of biologically active points is a significant increase in the number of white blood cells, which occurs due to lymphocytosis, and an increase in the number of red blood cells and neutrophils. Results obtained in this series of experiments, the data also allow to note that the introduction of the cerebrospinal fluid of cattle rabbits in the area of biologically active points results in significant (5-20%) increase in the number of bone marrow cells, including stimulating erythropoiesis, is preparation exhibits erythropoietic properties.
   
Keywords: cells, bone marrow, rabbits, hemapoiesis
   
   
   
Title:

DYNAMICS OF GROWTH, IMMUNOLOGICAL AND METABOLIC PROCESSES AT BULL-CALVES IN THE CONDITIONS OF THE APPLICATION OF NEW BIOGENIC COMPOUNDS

   
Authors: Yakovlev G.A., Shukanov └.A.
   
Address: Chuvash State Pedagogical University named after Yakovlev I.Ya.
   
Abstract: It is revealed the positive morphophysiological effects of an organism in the conditions of a combined application of  źSedimin-Se+╗ with źTrepel╗.
   
Keywords: oxen, immunogenesis, metabolism, źSedimin-Se+╗, źTrepel╗